Dr Ian Wright
MBBS (University of Newcastle-upon-Tyne) DCH (Royal College of
Physicians of London) MRCP FRACP
Conjoint Senior Lecturer in Paediatrics
and Child Health, University of Newcastle
Contact Details
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Senior
Staff Specialist in Neonatal Medicine Kaleidoscope
Neonatal Intensive Care Unit
Postal Address.
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.........61 (0) 249 214362
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Research Interests
Having trained in Paediatrics in the U.K., I sub-specialised in neonatal medicine. I have a strong background in academic neonatal medicine, undertaking my research training with Professor Malcolm Levene in Leeds. . I have experience at a senior level in major teaching hospitals in the UK, New Zealand and Australia, holding specialist qualifications in both the U.K. and Australia. I have been involved at these sites in the running of research studies ranging from physiology studies through to international multi-centred trials and thus have extensive experience of the difficulties of recruitment and involvement of sick neonates in clinical trials. Most of my research has examined aspects of cardiovascular function in neonates. In particular I have experience of a variety of vascular flow methods, including Ultrasonic Doppler, laser Doppler, flow probes (in animals) and xenon cerebral blood flow, which I commenced with Professor Malcolm Levene during my research fellowship in Leeds. I continued my interest in neonatal cardiovascular adaptation through my time as Neonatal Senior Lecturer in Auckland and to my current post in Newcastle.
I am now a part of the Mothers and Babies Research Centre of the Hunter Medical Research Institute, directed by Professor Roger Smith and I have developed the project of the effect of gender on neonatal cardiovascular adaptation with Dr Vicki Clifton. This work has been developed from work that we have done looking at the mechanisms of microvascular control in pregnancy and the effects of preeclampsia. I have been responsible for the micro vascular part of these studies. Local competitive grants and an equipment grant from local industry (2000-4) have funded this work, which has recently been performed as part of the PhD of Dr Michael Stark and has lead to international recognition, prize awards and several publications.
I work 100% of my time as a Senior Staff Specialist Neonatologist and as conjoint Senior lecturer the Faculty of Health of the University of Newcastle, but consider research to be an integral part of that work. I supervise 1 PhD student, and have supervised 2 Honours students and two summer studentships. I am actively involved in encouraging research participation by junior medical, nursing and allied health staff.
I am currently local coordinator for several national and international studies aimed at improving outcomes for the sick or preterm infant including the ICE trial (NHMRC ID:216725), BOOST2 (NHMRC ID: 352386) and I am an Associate Investigator on The Bubbles for Babies trial of level 2 CPAP (NHMRC ID:253790) and DAISY trial of developmental outcomes of surgical infants (March of Dimes, US, funded)
Other academic activities:
I have been a reviewer for a number of journals including Archives of Disease in Childhood, Journal of Paediatrics and Child Health, Journal of Clinical Endocrinology and Metabolism, American Journal of Physiology: Heart and Circulatory Physiology, American Journal of Physiology: Regulatory, Integrative and Comparative Physiology, Journal of Pediatrics and the McMasters Online Rating of Evidence System.
I have reviewed grants for the Australian Heart Foundation.
Memberships
Fetal and Neonatal Physiology Society ( Australia)
Fetal and Neonatal Physiology Society ( International)
IMPACT -Perinatal trials collaborative group
Royal Australasin College of Physicians, Paediatrics and Child Health Division
European Society of Paediatric Research
European Society of Microcirculation
Australian Society of Microcirculation
Publications
1. Ascariasis- picture case report. Wright I M R. BMJ 1990; 300: 1666.
2. Congenital Parvovirus Infection. Wright IMR , Williams ML. Archives of Diseases in Childhood 1991; 66: 253-4.
3. Skin necrosis related pulse oximetry probe - caution in the very low birthweight infant. Wright IMR and Puntis JWL. British Journal of Intensive Care 1993;3:394-8.
4. "Pharmacologic management of neonatal cerebral ischaemia and hemorrhage: old and new directions - V S Miller" ( book review). Wright, Ian. Developmental Medicine and Child Neurology 1993; 35: 1125.
5. Use of non-child proof containers (letter). Wright IMR. BMJ 1993; 306: 578.
6. Umbilical cord clamping in preterm infants (letter). Wright IMR. BMJ 1993; 306: 578.
7. Blood pressure and blood volume in preterm infants . Wright IMR and Goodall SR. Archives of Disease in Childhood 1994; 70: F230.
8. Pulse oximetry in newborn babies (letter). Wright IMR and Puntis JWL. Lancet 1994; 343: 1500.
9. Stethoscope contamination in the neonatal intensive care unit. Wright IMR, Orr H, Porter C. Journal of Hospital Infection 1995; 29: 65-68.
10. Prevention of intraventricular haemorrhage in preterm infants in Britain and Ireland. Wright IMR. Archives of Disease in Childhood 1995; 71: F79.
11. Is informed consent for neonatal trials an elaborate ritual? Levene MI, Wright IMR and Griffiths G. Lancet 1996; 347: 475.
12. The use of blue and black cohosh in labour. Gunn TR and Wright IMR. New Zealand Medical Journal Sept 1996
13. Periventricular Leucomalacia. Wright IMR. Neonatal Monitor. 1996; 14: 9 - 12.
14. Neonatal effects of maternal consumption of blue cohosh, Wright IM. Journal of Pediatrics. 134(3):384-5, 1999
15. Post transfusion leucocytosis in the sick neonate. Wright IMR, Skinner AM. Journal of Paediatrics and Child Health. Feb 2000
16. Microvascular effects of corticotropin-releasing hormone in human skin vary in relation to estrogen concentration during the menstrual cycle.
Clifton VL, Crompton R, Read MA, Gibson PG, Smith R, Wright IM.
J Endocrinol. 2005 Jul;186(1):69-76.17. Prenatal predictors of chronic lung disease in very preterm infants .
Henderson-Smart DJ, Hutchinson JL, Donoghue DA, Evans NJ, Simpson JM, Wright I; Australian and New Zealand Neonatal Network.
Arch Dis Child Fetal Neonatal Ed. 2006 Jan;91(1):F40-5. Epub 2005 Aug 30.18. Maternal microvascular response to corticotrophin releasing hormone (CRH) is altered by gestation, fetal gender, and pre-eclampsia
Stark MJ, Dierkx L, Clifton VL, Wright IMR,
Journal of the Society for Gynecologic Investigation Feb 2006; 13(2):13119. CPAP use in babies with respiratory distress in Australian nurseries.
Buckmaster AG, Arnolda G, Wright IMR, Henderson-Smart DJ.
Journal of Paediatrics and Child Health, accepted Sept 200620. Practice variation in initial management and transfer thresholds for infants with respiratory distress in Australian hospitals. Who should write the guidelines? Buckmaster AG, Wright IMR, Arnolda G, Henderson-Smart DJ.
Journal of Paediatrics and Child Health, accepted Oct 200621. Alterations in the Maternal Peripheral Microvascular Response in Pregnancies Complicated by Pre-eclampsia and the Impact of Fetal Sex
Stark MJ, Dierkx L, Clifton VL, Wright IMR
Journal of the Society for Gynecologic Investigation Nov 200622. A previously undescribed form of congenital disorder of glycosylation with variable presentation in siblings: Early fetal loss with hydrops fetalis, and infant death with hypoproteinemia.
McKenzie FA, Fietz M, Fletcher J, Smith RLL, Wright IMR, Jaeken J.
American Journal of Medical Genetics, accepted Mar. 2007.23. Cautionary tales from the neonatal intensive care unit: nappies may mislead urinary output estimation in extremely low birthweight infants
M Amey, N Butchard, L Hanson, D Kinross, M Mannion, J Parsons, IMR Wright
Pediatric Critical Catre Medicine, accepted April 200724. CPAP for Infants with Respiratory Distress in Non-Tertiary Care Centers.
A Randomized Controlled Trial.
Buckmaster, Adam G., Arnolda, Gaston, Wright, Ian M.R., Foster, Jann P., Henderson-Smart, David J. Accepted Pediatrics April 2007
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